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Standardized Cup Sizes
Breast Size 32aa
Celebrity example Mena Suvari
Breast Size 34A
Celebrity example Audrey Hepburn
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Cholesterol levels and use of lipid-lowering drugs are not associated with breast cancer risk
Cholesterol levels and use of lipid-lowering drugs are not
associated with breast cancer risk
October 25, 2005
CHICAGO - Cholesterol levels and use of statins or other
lipid-lowering drugs are not associated with breast cancer risk,
according to a study in the October 24 issue of Archives of
Internal Medicine, one of the JAMA/Archives journals.
Although some evidence suggests that statins (the most commonly
used type of lipid-lowering drugs) may inhibit tumor development
and may work in combination with chemotherapy drugs against cancer,
studies on the association between the use of statins and breast
cancer have had conflicting results, according to background
information in the article.
A. Heather Eliassen, Sc.D.
, of the Brigham and Women's Hospital,
Boston, Mass., and colleagues analyzed data from the Nurses' Health
Study to evaluate the associations of statins, lipid-lowering drugs
and serum cholesterol levels (blood levels of cholesterol) with
breast cancer. Serum cholesterol levels and use of statins and
lipid-lowering drugs were determined for 79,994 women through
questionnaires completed in 1988, 1994, 1996, 1998 and 2000. Cases
of breast cancer, diagnosed from the start of follow-up (1988)
through May 31, 2000, were identified on biennial questionnaires.
Medical records were used to confirm cancer reports.
There were 3,177 incident cases of invasive breast cancer,
including 1,727 in the analysis among statin users. Neither current
nor long-term use of statins nor other lipid-lowering drugs were
associated with breast cancer risk, the researchers report. There
was no association between reported total serum cholesterol levels
and breast cancer risk in either pre-menopausal or post-menopausal
women.
"In summary, the results of this study suggest that the
beneficial effect of statins on breast cancer observed in
experimental studies may not be applicable to humans," the authors
conclude. "We also found no associations of general lipid-lowering
drugs and serum cholesterol levels with breast cancer risk. Further
study is warranted to evaluate the associations of longer durations
of statin use and specific types of statins with breast cancer
risk."
JAMA and Archives Journals
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